My Journey started in December 2001 when i suffered my first Miscarriage at 10 weeks on Boxing Day, we were devestated but like many others were told that 1 in 4 first pregnancies end in miscarriage so put it down to bad luck, 6 months later i fell pregnant again but at 10 weeks suffered my 2nd Miscarriage. We were lucky in that the hospital i was with at the time actually conducted investigations after 2 miscarriages, so i had tests for the following

Chromosomal analysis
Lupus anticoagulant and anticardiolipin antibodies (antiphospholipidsyndrome) &
Hormonal blood tests, all of which came back negative.
With no know cause we decided to wait a while before trying again. I fell pregnant for the 3rd time in December 2003, this time i was monitored on a weekly basis and took a low dose of aspirin daily, but i started to bleed at 8 weeks, an ultrasound showed a baby and heartbeat that only measured 6.5 weeks, sadly a week later i suffered my 3rd loss.

I gave my consent for fetal karyotyping, which showed nothing untoward, and had a suspected partial molar pregnancy but this turned out to be unfounded as a second opinion ruled it out. At this point I felt like i had hit a brick wall as i had recieved all the available investigations conducted by the NHS which had all indicated that there was nothing wrong with either myself or my partner.

We decided to take a break again but to my shock i fell pregnant shortly after, totally unplanned and unexpected but still welcomed to say the least. I booked myself into our now nearest EPAU and went for a scan, we saw a baby with hb measuring correct for dates and we were on cloud nine. However this happiness was shortlived as we went back the following week for a further scan only to face the devestating news that once again our baby had gone, this time i had suffered a missed mc in the space of 6 days, i was gutted. I was re-referred for all the standard mc tests and also had an additional one, a thrombophilia screen, which was repeated twice due to borderline results. Again no answers or no known cause.

In February 2005 (16 months after my 4th loss) we agreed to try again. I came across information regarding a possible link between high levels of uterine natural killer cells and recurrent miscarriage whilst browsing the internet.

The theory had not yet been proven so Cinical trials at Liverpool womens hospital were being conducted using women with similar history to myself. I contacted my consultant who was reluctant at first but after 4 months decided he would refer me to Dr Quenby In Liverpool.

I made the Journey to Liverpool Womens Hospital in July 2005 and underwent a womb biopsy, the results of which showed that i had 5 times the 'normal' level of natural killer cells in my womb, which meant I was elligible for the trial treatment.

In October 2005 i fell pregnant for the 5th time and travelled to Liverpool again for a scan which showed a perfect yolk sac measuring the exact gestation it should. I was prescribed with a steroid called Prednisalone, and took decreasing amounts of the drug over the following 8 weeks. My Obstetric care was handed over to my consultant, who monitored me week by week up to 17 weeks, followed by growth scans at 30 and 32 weeks, the pregnancy went smoothly with no problems and the rest as they say is History...........

After 5 years and 4 heart breaking miscarriages i finally gave birth to our Daughter Madelyn Rose on June 20th 2006, she is perfect in every way. I am so grateful to Dr Quenby and her team in Liverpool for allowing me to take part in their trial, and if it hadn't been for them i wouldn't have my little girl with me today XXXXX